SHARING OF WORLDWIDE DISTRIBUTED CARBOHYDRATE-RELATED DIGITAL RESOURCES: ONLINE CONNECTION OF THE BACTERIAL CARBOHYDRATE STRUCTURE DATABASE AND GLYCOSCIENCES.DE

Ph. Toukacha, H. Joshib, R. Ranzingerb, Yu. Knirela, C.-W. von der Liethb

aN. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia,
bGerman Cancer Research Center, Spectroscopic Department, Heidelberg, Germany

KEYWORDS: structure,glycomics,glycoconjugate,bioinformatics,carbohydrate,computer,database,taxonomy,bibliography,programming interface,cross-search,BCSDB,GLYCOSCIENCES.DE

Nucleic Acid Research - Database Issue, 2007, v.35, pp.D280-D286

DOI: 10.1093/nar/gkl883    (free full text)


Functional glycomics, the scientific attempt to identify and assign functions to all glycan molecules synthesized by an organism, is an emerging field of science. In recent years, several databases have been started, all aiming to support deciphering the biological function of carbohydrates. However, diverse encoding and storage schemes are in use amongst these databases, significantly hampering the interchange of data. The mutual online access between the Bacterial Carbohydrate Structure DataBase and the GLYCOSCIENCES.de portal, as a first reported attempt of a structure-based direct interconnection of two glyco-related databases is described. In this approach, users have to learn only one interface, will always have access to the latest data of both services, and will have the results of both searches presented in a consistent way. The establishment of this connection helped to find shortcomings and inconsistencies in the database design and functionality related to underlying data concepts and structural representations. For the maintenance of the databases, duplication of work can be easily avoided, and will hopefully lead to a better worldwide acceptance of both services within the community of glycoscienists. BCSDB is available at http: //csdb.glycoscience.ru/bacterial/ and the GLYCOSCIENCES.de portal at http://www.glycosciences.de/


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